In Silico Trials

Reduce, Refine, and partially Replace Human and Animal Trials

Computational modelling & simulations

  • carefully engineer medical product innovations,

  • explicitly optimise clinical outcomes, and

  • thoroughly assess side effects before being marketed


  • Better Patient Outcomes

  • Less Risk to Patients

  • Better Device Designs

  • Fail Faster and Earlier

  • Reduce R&D Costs

  • Reduced Animal Harm

Trials on Real vs In Silico Patients - an exemplar

A typical Randomised Controlled Trial (RCT) of a cardiovascular device can take 6 to 8 years from design to publication, and cost £40-80m. Such a device can go to market with testing on less than 500 patients

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